1. Home
  2. Package
  3. EAWAG-SOIL - 2025-04-29 19:24
  4. Pathway
  5. Lenacil

Lenacil

Graphical Representation

Description

The main degradation pathways involved oxidation of the cyclopentapyrimidine moiety to IN-KF313 (3-cyclohexyl-6,7-dihydro-7-1H-cyclopentapryrimidine-2,4,5(3H)-trione) and oxidation of the cyclohexane moiety to IN-KE121 followed by oxidation of both degradates to carbon dioxide. The major degradation product metabolite IN-KF313 reached maximum level of 14.7% AR after 14 days; Metabolite IN-KE121 reached maximum level of 13.9% AR after 14 days. Polar components were found up to 11.9% of the applied radioactivity.