Spiroxamine was degraded in soil via dealkylation of the amine moiety forming KWG 4168- despropyl (M02) (maximum formation 9.2 %, at four following sampling times above 5 %) and KWG 4168-desethyl (M01) (maximum formation 7.9 %, at four following sampling times above 5 %). Both metabolites were present in relatively similar quantities and were decreasing after approximately 1-2 months. The high amount of carbon dioxide representing the final degradation product indicated mineralisation of spiroxamine in soil. The pattern of identified and unknown radiolabelled compounds revealed a permanent degradation of spiroxamine and of KWG 4168-despropyl (M02) and KWG 4168-desethyl (M01) leading to only minor intermediates. Bound residues were formed immediately after application but they were also degradable and reached a maximum at approximately day 88.