2-unsubstituted Cyclic ether > 2-Hydroxy cyclic ether

[#6:5]-[#6:1]([H])([H])@-[#8:4]@-[#6:2]>>[#6:2]@-[#8:4]@-[#6:1]([H])(-[#6:5])-[#8]([H])

[#6:5]-[#6:1]([H])([H])@-[#8:4]@-[#6:2]

None

[#6:2]@-[#8:4]@-[#6:1]([H])(-[#6:5])-[#8]([H])

None