2-Phenylacyl derivative → Catechol derivative + Acyl derivative<br><br>Comments:<br>This rule handles the 2-phenylacyl dioxygenation pathway and includes CoA ligation to the acyl (acetyl or 2-propanyl) substituent, 1,2-dioxygenation, elimination of acyl-CoA, and formation of the catechol derivative, based on <a href="http://www.ncbi.nlm.nih.gov/pubmed/16204529">Murdoch and Hay (2005)</a> and a review by <a href="http://www.ncbi.nlm.nih.gov/pubmed/19245937">Kagle et al. (2009)</a>.