2- or 3- substituted Carboxylate → RH + CO<sub>2</sub><br><br>Comments:<br>Will decarboxylate most 2-amino, 2-aryl, 2-tertiary carbon, 2-N-heterocyclic aromatic, 3-keto, 3-ene-5-keto, 3-hydroxy, and 3-aryl carboxylates. Handles most appropriate microbial IUBMB <a href="http://www.enzyme-database.org/query.php?ec=4.1.1.*">EC4.1.1.-</a> decarboxylations, including alterative substrates. Will not act on substrates for beta-oxidation (bt0337), alpha-hydroxy acids.
